Диеты и лечебное голодание.

[Вадим Асадулин.]

Am J Clin Nutr. 2008 Sep.
Association of vegetable, fruit, and grain intakes with colorectal cancer: the Multiethnic Cohort Study.
Nomura AM, Wilkens LR, Murphy SP, Hankin JH, Henderson BE, Pike MC, Kolonel LN.
Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA. [e-mail]
BACKGROUND: It is uncertain whether or not vegetables, fruit, or grains protect against colorectal cancer. OBJECTIVE: In a large prospective study, we investigated the association of vegetable, fruit, and grain intakes with colorectal cancer risk. DESIGN: Between 1993 and 1996, 85 903 men and 105 108 women completed a quantitative food-frequency questionnaire that included approximately 180 foods and beverages in the Multiethnic Cohort Study. A diagnosis of colorectal cancer was made in 1138 men and 972 women after an average follow-up of 7.3 y. Cox proportional hazards models were used to calculate multivariate-adjusted relative risks and 95% CIs for colorectal cancer. RESULTS: In men, multivariate adjustment for energy intake, dietary, and nondietary variables resulted in relative risks in the highest quintile group of 0.74 (95% CI: 0.59, 0.93; P for trend = 0.02) for vegetables and fruit combined, 0.80 (95% CI: 0.64, 0.99; P for trend = 0.09) for fruit alone, and 0.85 (95% CI: 0.69, 1.05; P for trend = 0.05) for vegetables alone. When colon and rectal cases were separated among men, the inverse associations were stronger for colon than for rectal cancer. In women, none of the associations with vegetables, fruit, or vegetables and fruit combined were significant. Grain intake was not associated with colorectal cancer for either men or women. CONCLUSION: The intake of vegetables and fruit was inversely related to colorectal cancer risk among men but not among women. The association appears stronger for colon than for rectal cancer.
http://www.ncbi.nlm.nih.gov/pubmed/1877 ... d_RVDocSum

[Вадим Асадулин.]

BMJ. 2003 Oct.
Dietary fat intake and risk of stroke in male US healthcare professionals: 14 year prospective cohort study.
He K, Merchant A, Rimm EB, Rosner BA, Stampfer MJ, Willett WC, Ascherio A.
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA. [e-mail]
OBJECTIVE: To examine the association between intake of total fat, specific types of fat, and cholesterol and risk of stroke in men. Design and setting Health professional follow up study with 14 year follow up. PARTICIPANTS: 43 732 men aged 40-75 years who were free from cardiovascular diseases and diabetes in 1986. MAIN OUTCOME MEASURE: Relative risk of ischaemic and haemorrhagic stroke according to intake of total fat, cholesterol, and specific types of fat. RESULTS: During the 14 year follow up 725 cases of stroke occurred, including 455 ischaemic strokes, 125 haemorrhagic stokes, and 145 strokes of unknown type. After adjustment for age, smoking, and other potential confounders, no evidence was found that the amount or type of dietary fat affects the risk of developing ischaemic or haemorrhagic stroke. Comparing the highest fifth of intake with the lowest fifth, the multivariate relative risk of ischaemic stroke was 0.91 (95% confidence interval 0.65 to 1.28; P for trend = 0.77) for total fat, 1.20 (0.84 to 1.70; P = 0.47) for animal fat, 1.07 (0.77 to 1.47; P = 0.66) for vegetable fat, 1.16 (0.81 to 1.65; P = 0.59) for saturated fat, 0.91 (0.65 to 1.28; P = 0.83) for monounsaturated fat, 0.88 (0.64 to 1.21; P = 0.25) for polyunsaturated fat, 0.87 (0.62 to 1.22; P = 0.42) for trans unsaturated fat, and 1.02 (0.75 to 1.39; P = 0.99) for dietary cholesterol. Intakes of red meats, high fat dairy products, nuts, and eggs were also not appreciably related to risk of stroke. CONCLUSIONS: These findings do not support associations between intake of total fat, cholesterol, or specific types of fat and risk of stroke in men.
http://www.ncbi.nlm.nih.gov/pubmed/1452 ... stractPlus

[Вадим Асадулин.]

Я никогда не рекомендовал питание по группам крови, считая это шарлатанством. Но знакомство с объективной информацией показало, что всё не так однозначно, как утверждают представители академической медицины и пропагандисты этих диет.

Лектины, содержащиеся в продуктах питания, - одна из основных причин нарушения хрупкого равновесия желудочно-кишечного тракта. Действие лектинов, имеющих белковую природу, зависит от группы крови. Если в пище, которую вы едите, содержатся несовместимые с вашей группой крови лектины, то они будут нарушать работу желудочно-кишечного тракта и иммунной системы, а также обмен веществ.

http://www.fit-area.com/adamo_6.shtml


Tidsskr Nor Laegeforen 2001 Jun. Scientific basis of the blood group diet. Article in Norwegian. Poleszynski DV.
[e-mail]
ABSTRACT: Eat Right 4 Your Type by Peter J. D’Adamo describes a strategy of adapting lifestyle and nutrition to each individual’s physiology and biochemistry. The author’s theory is based on research within, amongst others, physical anthropology, neurology, biochemistry, nutrition, lectinology, epidemiology, psychology, immunology and genetics. Going through the literature shows that Doctor D’Adamo can be mistaken on certain points, and is vague on others. Nonetheless, his general theory seems to be based on scientific studies, and reports show that it works. “Helsevesenet” - the Public Norwegian Health Institutions - should start using the parts of the theory that are based in fact, and the medicinal circles should do more testing and align the theory with basic medicinal science and clinical research.
http://www.dadamo.com/knowbase/citations/citation1.html

Altern Med Rev. 2001 Aug.
Metabolic and immunologic consequences of ABH secretor and Lewis subtype status.
D'Adamo PJ, Kelly GS.
Determining ABH secretor phenotype and/or Lewis (Le) blood group status can be useful to the metabolically-oriented clinician. For example, differences in ABH secretor status drastically alter the carbohydrates present in body fluids and secretions; this can have profound influence on microbial attachment and persistence. Lewis typing is one genetic marker which might help identify subpopulations of individuals genetically prone to insulin resistance, autoimmunity, and heart disease. Understanding the clinical significance of ABH secretor status and the Lewis blood groups can provide insight into seemingly unrelated aspects of physiology, including variations in intestinal alkaline phosphatase activity, propensities toward blood clotting, reliability of some tumor markers, the composition of breast milk, and several generalized aspects of the immune function. Since the relevance of ABH blood group antigens as tumor markers and parasitic/bacterial/viral receptors and their association with immunologically important proteins is now well established, the prime biologic role for ABH blood group antigens may well be independent and unrelated to the erythrocyte.
http://www.ncbi.nlm.nih.gov/pubmed/1157 ... t=Abstract

Med Sci Monit. 2002 Dec.
Lectins as markers for blood grouping.
Khan F, Khan RH, Sherwani A, Mohmood S, Azfer MA.
Genetics Section, Department of Zoology, AMU, Aligarh, India.
Lectins are unique proteins of varying biological importance. They are characterized by specific binding to carbohydrate residues, whether monosaccharides, disaccharides or polysaccharides. The sugar heads on the surface of the erythrocyte specify the different blood groups. Lectins, as an antigenic determinant of blood group, have come to be an important tool in the identification of different blood groups. A handful of lectins may be considered excellent reagents for anti-A, anti-B, anti-N etc, but the anti-A and anti-M are not yet regarded as commercially suitable antisera. Lectin from Vicia cracca has been proved to be a good anti-A, lectin from Dolichus biflorus can be used as anti-A1, and lectin from Griffonia simplicifolia as anti-B. Lectin from Vicia graminea is said to be a good typing reagent as Anti-N. On the other hand, the lectins involved in polyagglutination are absolutely essential as the reagent of choice and these cannot as yet be replaced by antibodies of any kind. Erythrocytes with exposed cryptantigens are significantly more sensitive to agglutination by certain lectins than by polyclonal antibodies. Peanut agglutinin (PNA), Polybrene, and Glycine max lectins are frequently used for the identification of different cryptantigens. The application of lectins as an anti-B reagent has proven to be as useful as human polyclonal or mouse monoclonal antibodies. Besides their specificity, lectins are excellent reagents because of their lower cost and indigenous production. The importance of various lectins used as markers for blood grouping is discussed.

Набрал в PubMed ‘ABO blood groups DIET’
получил 46 противоречивых ссылок.

Вот несколько, без резюме, как будто специально, для сокрытия информации, требуется поиск полных статей оригиналов.
Lakartidningen. 2004 Oct 7. Blood group diet: fantasy and quackery. Article in Swedish.
Nylun KD, Sjölin K, van der Ster G, Larhammar D.
Dietistprogrammet, Uppsala universitet.
PMID: 15517716 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/1551 ... d_RVDocSum

Tidsskr Nor Laegeforen. 2002 May 30.
Blood type diet--visionary science or nonsense? Article in Norwegian.
Meltzer HM, Haugen M, Haavardsholm KC, Hagen KB, Heier HE, McKellep AM, Glørstad H, Tandberg A.
Divisjon for miljømedisin Nasjonalt folkehelseinstitutt Postboks 4404 Nydalen 0403 Oslo. [e-mail]
PMID: 12098911 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/1209 ... rom=pubmed
Blood type diet:
http://en.wikipedia.org/wiki/Blood_type ... h_evidence

Есть ли у кого опыт применения этих диет и практические результаты?

[Вадим Асадулин.]

Доказана генетическая связь сахарного диабета 1 типа и целиакии
Сахарный диабет 1 типа (СД1) - наследственное заболевание, возникающее в результате деструкции инсулин-продуцирующих β-клеток островков поджелудочной железы. СД1 болеют приблизительно 0,4% европейцев. СД1 ассоциирован с определенными генами системы HLA, локализующимися на двух локусах хромосомы 6p21 (HLA-DQB1 и HLA-DRB1), а также с другими генами, не относящимися к системе HLA, и факторами окружающей среды.
Целиакия (Ц) - аутоиммунное заболевание, обусловленное неспособностью тонкого кишечника переваривать глютен, содержащийся в злаковых (ячмень, рожь, пшеница) вследствие недостаточности фермента трансглютаминазы. Ц страдают по крайней мере 0,1% жителей Северной Европы. Это заболевание также ассоциировано с наличием гена HLA-DQB1. Ц чаще встречается у лиц, страдающих СД1, чем в общей популяции (по крайней мере 10% детей и 2% взрослого населения с СД1 имеют антитела к трансглютаминазе). Предполагается, что потребление глютена в сочетании с воспалением и повышенной проницаемостью кишечной стенки, являются факторами развития СД1. Европейские ученые попытались доказать, что в развитии Ц и СД1 имеются некоторые общие причинные генетические факторы и факторы окружающей среды.
http://www.medicusamicus.com/index.php?action=1x1589x1

[Анна Нико]

Что же вы начинаете на друг друга "гнать"? powerz в организме гиперхолестеринемия может возникнуть не только на фоне повышенного потребления жиров, но и из-зи нарушения обмена липидов .Ведь с экзогенным холестерином организм вполне может справиться, если нет нарушения обмена веществ.Кстати даже на вскрытии 6-месячных детей можно найти в сосудах жировые пятна-предвестники атеросклероза.

[2w_ink]

Анна Нико в сообщении #195618 писал(а):

Кстати даже на вскрытии 6-месячных детей можно найти в сосудах жировые пятна-предвестники атеросклероза.

вероятно продиктовано симультантной предрасположенностью матери?