Сделал подборку из PubMed про мумиё. Есть ли у кого выход на статьи, можно сделать неплохой обзор.
Phytother Res. 2007 Feb 13. Shilajit: a review.
Agarwal SP, Khanna R, Karmarkar R, Anwer MK, Khar RK.
Department of Pharmaceutics, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.
Shilajit is a pale-brown to blackish-brown exudation, of variable consistency, exuding from layers of rocks in many mountain ranges of the world, especially the Himalayas and Hindukush ranges of the Indian subcontinent. It has been found to consist of a complex mixture of organic humic substances and plant and microbial metabolites occurring in the rock rhizospheres of its natural habitat. Shilajit has been used as a rejuvenator and an adaptogen for thousands of years, in one form or another, as part of traditional systems of medicine in a number of countries. Many therapeutic properties have been ascribed to it, a number of which have been verified by modern scientific evaluation. Shilajit has been attributed with many miraculous healing properties.
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J. Ethnopharmacol. 2006 Oct 11;107(3):349-53. Epub 2006 Apr 18.
The spermatogenic and ovogenic effects of chronically administered Shilajit to rats.
Park JS, Kim GY, Han K.
College of Pharmacy, Chungbuk National University, Cheongju, Heungdukgu Gaeshindong San 12, Chungbuk 361-763, South Korea.
This study examined the possibility of using Shilajit as a fertility agent. The effects of Shilajit on spermatogenesis and ovogenesis were studied using male and female rats. Shilajit was administered orally to 7-week-old rats over a 6-week period. In the male rats, the number of sperms in the testes and epididymides was significant higher than in the control. A histological examination revealed an apparent increase in the number of seminiferous tubular cell layers in the testes of the treated rats. However, there were no significant differences in the weights of heart, spleen, liver, kidney, brain, testes and epididymides. In the female rats, the effect of Shilajit was estimated by the ovulation inducing activity. Over a 5-day, ovulation was induced in seven out of nine rats in the Shilajit administration group and in three out of nine rats in the control. It was estimated that Shilajit had both a spermiogenic and ovogenic effect in mature rats.
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Phytother Res. 2001 Mar;15(2):177-9.
Effects of Shilajit on the development of tolerance to morphine in mice.
Tiwari P, Ramarao P, Ghosal S.
Faculty of Pharmacy and Medical Sciences, Post Box No. 232, Amman University, Amman 19328, Jordan.
vndna@firstnet.com.jo
Effects of concomitant administration of Processed Shilajit (PS, 0.1 and 1 mg/kg, i.p.), in Swiss mice were evaluated on the development of tolerance to morphine induced analgesia in the hot plate test. Chronic administration of morphine (10 mg/kg, i.p., b.i.d.) to mice over a duration of 10 days resulted in the development of tolerance to the analgesic effect of morphine. Concomitant administration of PS with morphine, from day 6 to day 10, resulted in a significant inhibition of the development of tolerance to morphine (10 mg/kg, i.p.) induced analgesia. Processed Shilajit per se, in the doses used, did not elicit any significant analgesia in mice; nor did the chronic concomitant administration of Processed Shilajit alter the morphine-induced analgesia. These findings with Processed Shilajit indicate its potential as a prospective modifier of analgesic tolerance to morphine.
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Drug Dev Ind Pharm. 1998 Nov;24(11):1109-12.
Preliminary evaluation of shilajit as a suspending agent in antacid suspensions.
Shahjahan M, Islam I.
Drug Control Authority, Safat, Kuwait.
The efficacy of shilajit, a gummy exudate of the plant Styrax officinalis Linn (Family: Styraceae), was evaluated as a suspending agent for the formulation of antacid preparations. Shilajit produced effects on sedimentation volume similar to those produced by sodium carboxymethyl cellulose (CMC), but at lower concentrations. It induced better flocculation with a moderate increase in viscosity compared to CMC. It did not interfere with the acid-consuming capacity of the suspensions.
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J. Ethnopharmacol. 1990 Apr;29(1):95-103.
Antiulcerogenic and antiinflammatory studies with shilajit.
Goel RK, Banerjee RS, Acharya SB.
Department of Pharmacology, Banaras Hindu University, Varanas, India.
In folk medicine, shilajit has been used to treat diverse clinical conditions ranging from peptic ulcer to bone healing. The present study was conducted to evaluate the possible antiulcerogenic and antiinflammatory activities of shilajit obtained from the rocky mountains of Zarlek, Badekshan, Afghanistan. Shilajit increased the carbohydrate/protein ratio and decreased gastric ulcer index, indicating an increased mucus barrier. Shilajit was found to have significant antiinflammatory effect in carrageenan-induced acute pedal oedema, granuloma pouch and adjuvant-induced arthritis in rats. The results of the present study thus substantiate the use of shilajit in peptic ulcer and inflammation.
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Вот ещё только названия статей:
Indian J. Exp Biol. 1988 Oct;26(10):775-7.
Pharmacological actions of Shilajit. Acharya SB, Frotan MH, Goel RK, Tripathi SK, Das PK.
J. Pharm Sci. 1976 May;65(5):772-3. Shilajit I: chemical constituents. Ghosal S, Reddy JP, Lal VK.
Indian J. Physiol Pharmacol. 1965 Apr;9(2):87-92. Effect of Gurmar and shilajit on body weight of young rats. Gupta SS, Seth CB, Mathur VS.